综合训练改善了多发性硬化症患者的功能能力,疲劳和生活质量:系统性审查和元分析
Fereshteh Kazemi Pakdel1, Ahmad Kazemi Pakdel2, Hamed Zarei2
1Corrective Exercises and Sports Injury Department, Faculty of Physical Education & sport sciences, University of Guilan, Rasht, 4199613776, Iran. fereshteh.kazemi.pakdel@gmail.com.
BMC neurology
|December 4, 2025
概括
综合训练 (CT) 显著改善了多发性硬化症 (PwMS) 患者的肌肉力量,平衡,步态和生活质量. 这种运动方法也有效地减少了疲劳,为MS管理提供了一个整体的方法.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 运动科学 运动科学
背景情况:
- 多发性硬化症 (MS) 严重影响身体功能,包括力量,协调,步态和平衡.
- 目前的研究往往侧重于单一的炼方式,因此需要了解MS的综合训练 (CT) 的好处.
- CT干预为解决MS患者 (PwMS) 面临的多方面的挑战提供了一个有希望的途径.
研究的目的:
- 系统地审查和分析各种CT干预措施对PwMS关键结果的影响.
- 评估CT对肌肉力量,平衡,步行速度,耐力,疲劳和生活质量的影响.
- 提供基于证据的见解,以优化MS患者的康复策略.
主要方法:
- 在8个主要数据库中进行了系统的文献搜索,截至2025年7月25日.
- 包括的研究使用物理治疗证据数据库 (PEDro) 标准进行了质量评估.
- 使用标准化平均差异 (SMD) 和95%置信区间 (CI) 进行了元分析,以综合发现.
主要成果:
- 该审查包括了20项与577名参与者的研究,显示CT显著改善.
- CT对下肢肌肉强度 (SMD=1.04),平衡 (SMD=1.20),步行速度 (SMD=0.77) 和步行耐力 (SMD=0.96) 有积极影响.
- 在PwMS中观察到生活质量的显著改善 (SMD=0.69) 和疲劳的减少 (SMD=0.82).
结论:
- CT干预措施对MS患者的身体和功能结果产生了显著的积极影响.
- 这些发现支持CT作为改善力量,平衡,步态和生活质量的有效策略,同时减少疲劳.
- 将CT纳入临床实践可以加强康复,改善MS的整体福祉和管理.
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