儿科病毒化卵巢瘤:一个系统性审查
Shruthi Ravindra1, Satish Kumar Samal1, Melkunte Shanthaiah Dhananjaya1
1Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India.
Clinical endocrinology
|December 4, 2025
概括
病毒化卵巢瘤 (VOT) 在儿童中很罕见. 这一系统性审查突出了它们多样化的临床表现,荷尔蒙特征和年龄特定的组织学,强调了需要进一步研究的必要性.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 妇科瘤学 妇科瘤学
- 在瘤学瘤学.
背景情况:
- 病毒化的卵巢瘤 (VOT) 在儿科患者中很少见.
- 关于它们的临床谱,荷尔蒙特征,成像,组织学和结果的文献有限.
- 这项研究系统地审查了儿科VOT的特征.
研究的目的:
- 进行对儿科病毒化卵巢瘤 (VOT) 的系统审查.
- 分析临床谱,荷尔蒙特征,成像,组织学和儿科VOT的结果.
- 确定特定年龄的特征和潜在的管理策略.
主要方法:
- 按照PRISMA指南进行的系统审查.
- 搜索了PubMed和谷歌学者对儿科VOT (<20岁) 的英语报告,具有高雄性质和确定的组织学.
- 提取和分析人口统计,临床特征,激素概况,成像,组织学,管理和结果的数据.
主要成果:
- 包括117名患有VOT的儿科患者 (平均年龄:15岁).
- 常见的症状包括疹症 (73.5%),阴囊 (68.4%) 和月经不规则 (79名患者).
- 青春期颗粒细胞瘤和塞尔托利-莱迪格细胞瘤分别在年轻和年长的儿科组中最常见. 复发是罕见的.
结论:
- 在患有VOT的8岁以下儿童中,高雄性表现的频率较低.
- 升高的17-基孕 (17-OHP) 和/或脱乙硫酸 (DHEAS) 不排除VOT.
- 儿科VOT的病因谱是特定于年龄的,因此需要进一步的多中心研究来预后和管理.
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