在土耳其的炎症性肠病的三十年分析:一个多中心研究 (1993-2024)
Muhammed Bahaddin Durak1, Yasir Furkan Cagin2, Ayhan Balkan3
1Department of Gastroenterology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
炎症性肠道疾病 (IBD) 在土耳其正在上升,克罗恩氏病相对于性结肠炎的增加. 虽然生物治疗的使用和克罗恩病的发病率有所上升,但IBD的手术干预在过去的三十年里有所下降.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 内部医学 内部医学
背景情况:
- 炎症性肠病 (IBD) 是一个日益严重的全球健康挑战.
- 了解区域IBD趋势,特别是欧洲和亚洲之间的IBD趋势至关重要.
- 本研究研究了过去30年来土耳其IBD的发展模式.
研究的目的:
- 调查土耳其IBD的流行病学趋势和临床特征.
- 分析了30年来IBD流行率,患者人口统计和治疗方式的变化.
- 将土耳其的IBD模式与欧洲和亚洲地区观察到的IBD模式进行比较.
主要方法:
- 在土耳其的14个中心对4308名IBD患者进行了回顾性分析.
- 数据收集时间从1993年6月到2024年3月.
- 纳入标准包括性结肠炎和克罗恩病的诊断.
主要成果:
- 30年来,IBD的患病率有所增加,而性结肠炎与克罗恩病的比率有所下降.
- IBD发病的中位数年龄为34.43岁,克罗恩氏病的年龄 (32.72) 比性结肠炎的年龄 (35.52) 更小.
- 生物疗法使用率上升至36.6%,而主要的腹部手术减少,其中24.3%为克罗恩氏病而接受手术,3.5%为性结肠炎.
结论:
- 土耳其的IBD频率和特征将其置于欧洲和亚洲流行病学概况之间.
- 克罗恩病的患病率增加和生物疗法的使用增加标志着最近的趋势.
- 在研究期间观察到,IBD主要腹部手术的发生率显著下降.
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