糖尿病患者和没有糖尿病患者的全关节形术后的结果:一项TrinetX数据库研究
Kathleen Cummer1, Memrie Ferguson2, Georgiy Golovko3
1Department of Rehabilitation Medicine, The University of Washington, USA.
患有2型糖尿病 (T2DM) 的患者接受全部或膝盖关节整形手术,面临明显更高的并发症风险. 密切的术后监测对于T2DM患者来说至关重要,以减轻关节置换手术后的这些风险.
科学领域:
- 整形外科手术 整形外科手术
- 糖尿病学 糖尿病学
- 健康 结果 研究 研究 结果
背景情况:
- 糖尿病影响高达25%的患者接受全关节整形术 (THA) 或全膝关节整形术 (TKA).
- 在THA/TKA后的糖尿病患者和非糖尿病患者之间存在并发症率的变化.
研究的目的:
- 为了比较术后的结果,在THA或TKA后长达5年.
- 评估糖尿病患者和没有糖尿病患者并发症率的差异.
主要方法:
- 利用TrinetX数据库将患者分为2型糖尿病 (T2DM),1型糖尿病 (T1DM) 和没有糖尿病 (对照) 队列.
- 员工倾向匹配 (年龄,种族,种族) 进行可比的队列分析90天,2年,5年.
- 使用概率比率和置信区间评估结果.
主要成果:
- 与对照组相比,T2DM患者 (97,404) 的结果始终较差.
- 在90天后,T2DM患者的再入院率 (25.7%),麻醉下操纵 (12.5%) 和感染 (33%) 的几率更高.
- 在2年和5年后,T2DM患者的再入院率增加,修复关节整形术,切除关节整形术和远部大腿骨折.
结论:
- 接受THA/TKA治疗的T2DM患者面临明显更高的并发症几率.
- 与对照组相比,1型糖尿病 (T1DM) 患者的并发症没有显著差异.
- 对于T2DM患者来说,密切的术后监测是必不可少的,以尽量减少并发症风险.
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