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鼻腔灌的有效性与异和高压溶液在内镜鼻腔外科手术后慢性鼻炎与鼻腔多重症
Ana Penezić1,2, Livije Kalogjera1,3, Marko Velimir Grgić1,3
1Department of Otorhinolaryngology, Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Acta clinica Croatica
|December 4, 2025
概括
在进行内镜鼻手术 (ESS) 后,使用高度盐水和藻类提取物灌鼻,以治疗具有鼻多重症 (CRSwNP) 的慢性鼻炎,改善了症状,特别是打喷和,尽管与同盐水相比,这些症状在统计学上并不显著.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 鼻科 鼻科是指鼻科的专家.
- 医学研究 医学研究
背景情况:
- 具有鼻多重症的慢性鼻炎 (CRSwNP) 通常需要内镜性鼻手术 (ESS).
- 手术后的鼻灌对于ESS后的CRSwNP患者的愈合和症状管理至关重要.
研究的目的:
- 为了比较异性 (0.9% NaCl) 与高性 (2.3% NaCl) 盐水鼻灌的疗效,富含藻类提取物,在ESS后的CRSwNP患者中.
- 评估对鼻腔全症状评分 (TNSS) 和内镜隆德-肯尼迪 (LK) 评分的影响.
主要方法:
- 一项随机队列研究,涉及54名CRSwNP患者在ESS后.
- 患者被分配给接受同位素或高位素盐水与藻类提取物 (Undaria pinnatifida,Spirulina platensis) 的鼻灌.
- 使用TNSS的症状评估和使用LK得分的内镜评估在术前和术后的第7天和第14天进行.
主要成果:
- 这两种灌解决方案在术后第7天和第14天改善了TNSS和LK分数.
- 含藻类的高度溶液显示TNSS和LK得分有更大的改善趋势,但没有达到统计学意义.
- 在高血压组中,特定症状 (如打喷和) 显著改善.
结论:
- 鼻灌在ESS后对CRSwNP患者具有治疗性益处.
- 用藻类提取物丰富的高血压盐灌可能为ESS后的打喷和等特定症状提供增强的缓解.
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