肥胖中的肝激素调节:在肥胖男性中,哪种运动训练模式更好?
Ali Ataeinosrat1, Hossein Abednatanzi2, Shohreh Hajesfandiari2
1Department of Exercise Physiology, University of Tehran, Tehran, Iran.
Frontiers in endocrinology
|December 4, 2025
概括
高强度间歇训练 (HIIT) 和 Tabata 显著降低了肥胖标志物和诸如 fetuin-B 和 FGF-21 等关键肝激素. 这些运动干预措施为肥胖个体的代谢健康带来了有希望的好处.
科学领域:
- 运动生理学 运动生理学
- 代谢健康 代谢健康
- 肥胖问题研究研究
背景情况:
- 肥胖与代谢功能障碍和改变的肝激素分泌有关.
- 肝激素如 fetuin-A, fetuin-B, FGF-21, PAI-1, FGL1 和 selenoprotein P 在新陈代谢调节中发挥作用.
- 了解不同运动方式对这些标记物的影响对于管理与肥胖有关的并发症至关重要.
研究的目的:
- 为了比较12周连续有氧运动, Tabata 和 HIIT 对肥胖男性特定肝激素水平的影响.
- 为了评估不同运动干预后的 fetuin-A, fetuin-B, FGF-21, PAI-1, FGL1 和 selenoprotein P 的变化.
- 评估运动对体重,BMI和身体脂肪百分比的影响.
主要方法:
- 44名肥胖男性被随机分为四组:对照 (CT),耐力训练 (ET),Tabata和HIIT.
- 运动计划包括12周的每周三次60分钟的练习.
- 在干预期之前和之后,测量了肝激素,体重,BMI和身体脂肪.
主要成果:
- 对于fetuin-B,FGF-21,FGL-1,体重,BMI,%脂肪和蛋白P.观察到显著的分组时间相互作用.
- 与对照组相比,HIIT和Tabata组显示 fetuin-B 的减少更大.
- 与对照组相比,所有运动组 (ET,HIIT,Tabata) 显示FGF-21和FGL-1的显著减少.
结论:
- 12周的体力活动,特别是塔巴塔和HIIT,有效降低了体重,BMI,身体脂肪,fetuin-B,FGF-21,FGL-1和蛋白P.
- 在肥胖男性中,HIIT和Tabata成为改善这些代谢标记的更有效的干预措施.
- 运动训练是减轻与肥胖相关的代谢障碍的可行策略.
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