[来自ICONIC观测研究的阿根廷和智利数据分析]
Alicia Sambuelli1, Gustavo Walsen Arangua2, Juan Andrés de Paula3
1Centro de Estudios y Tratamiento de Enfermedades Inflamatorias (CEYTIN). Grupo médico del Consultorio de Enfermedades Inflamatorias del Intestino (CEIDI), Ciudad Autónoma de Buenos Aires, Argentina. Centro de Estudios y Tratamiento de Enfermedades Inflamatorias (CEYTIN) Grupo médico del Consultorio de Enfermedades Inflamatorias del Intestino (CEIDI) Ciudad Autónoma de Buenos Aires Argentina.
Acta gastroenterologica Latinoamericana
|December 4, 2025
概括
早期治疗减少了性结肠炎 (UC) 患者的痛苦. 疾病图像表示和自我测量 (PRISM) 工具有效量化了患者的痛苦,与其他UC结果措施相关联.
科学领域:
- 胃肠病学 胃肠病学
- 临床医学 临床医学
- 患者报告的结果
背景情况:
- 性结肠炎 (UC) 对患者构成重大负担.
- 评估患者的痛苦对于有效的UC管理至关重要.
- 疾病图像表示和自我测量 (PRISM) 工具提供了一种量化这种痛苦的方法.
研究的目的:
- 使用PRISM工具评估性结肠炎 (UC) 患者的痛苦负担.
- 评估PRISM得分与其他UC结果指标之间的相关性.
- 分析跨国队列中患者和医生报告的结果.
主要方法:
- 一项前性观察性研究 (ICONIC),包括33个国家最近出现UC的门诊患者.
- 收集患者和医生报告的结果,包括在基线和随访期间的PRISM,SIBDQ,PHQ-9和SCCAI/pSCCAI.
- 这项分析主要集中在阿根廷和智利的数据上.
主要成果:
- 总共有89名患者至少进行了一次随访.
- 疾病严重程度 (SCCAI/pSCCAI) 在24个月内显著下降 (p < 0.05).
- 通过PRISM测量患者和医生评估的痛苦显著减少,并且与改善的UC结果相关,尽管医生低估了患者报告的痛苦.
结论:
- 早期治疗UC与降低患者负担和痛苦有关.
- 由于其与其他评估尺度的相关性,PRISM工具是量化UC患者痛苦的有价值工具.
- 医生通过PRISM评估的痛苦可能低估了患者报告的痛苦水平.
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