评估用于诊断粘附性小肠阻塞的超块水溶性对比介质:随机对照试验的系统审查和元分析
Abdullah H Almeghthawi1, May S Alrawithi2, Zaher A Alshehri2
1Department of Surgery, College of Medicine, Taibah University, Madinah, SAU.
Cureus
|December 4, 2025
概括
超块水溶性对比剂 (HWSC) 显著减少住院时间和在粘性小肠阻塞 (ASBO) 患者手术的需要. 这一元分析证实了HWSC的存在.
科学领域:
- 胃肠病学 胃肠病学
- 放射学 放射学是一门学科.
- 手术瘤学手术瘤学
背景情况:
- 粘性小肠阻塞 (ASBO) 是一个常见的手术紧急情况.
- 在ASBO管理中,高度水溶性对比剂 (HWSC) 的治疗作用受到辩论.
- 预测在ASBO中需要进行手术对于患者的结果至关重要.
研究的目的:
- 系统地审查和元分析HWSC在诊断和管理ASBO中的有效性.
- 为了比较HWSC管理与ASBO的标准非操作管理.
- 评估HWSC对住院时间 (HLOS) 和手术率的影响.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 搜索了包括PubMed,谷歌学者和科学网在内的数据库.
- 包括12个随机对照试验 (1150名患者) 评估ASBO的HWSC.
主要成果:
- HWSC显著降低了HLOS,平均差异为-2.17天 (p=0.0001).
- 在HWSC中,手术需求减少了38% (RR=0.63,p=0.0002).
- 对于其他次要结果,没有发现显著差异.
结论:
- 在ASBO患者中,HWSC的使用有效地缩短了HLOS.
- 与传统的非手术护理相比,HWSC减少了手术干预.
- 需要进一步的研究来优化HWSC的剂量和时间表.
相关概念视频
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
353
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
353
Radiological Investigation I: X-ray and CT
1.0K
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
1.0K
Drugs Affecting GI Tract Motility: Other Laxatives
992
Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
992
Imaging Studies III: Computed Tomography
261
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
261
Drugs for Treatment of Constipation-Predominant IBS
680
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
680
Drugs for Treatment of Diarrhea-Predominant IBS
599
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
599


