在患有消化系统瘤的患者中,术后腹部内感染的风险预测模型:系统性审查
Yu Wang1, Li Wang2, Yunhong Du2
1School of Nursing, Hunan University of Chinese Medicine, Changsha, China.
Frontiers in oncology
|December 4, 2025
概括
在消化系统瘤患者中,术后腹内感染 (IAI) 是一个严重的风险. 目前的预测模型有希望,但需要进一步严格验证和标准化,用于临床使用.
科学领域:
- 在瘤学瘤学.
- 外科手术的结果
- 预测建模预测建模
背景情况:
- 手术后腹部内感染 (IAI) 是消化系统瘤患者的重要并发症,导致住院时间,费用和死亡率增加.
- 准确预测IAI对于及时干预和改善患者预后至关重要.
- 由于研究设计和数据来源的多样化,IAI现有的预测模型缺乏全面的评估.
研究的目的:
- 在患有消化系统瘤的患者中,系统地审查和评估术后腹内感染 (IAI) 的现有预测模型.
- 为IAI提供优化或开发新的结构化预测模型的基础.
- 评估该患者群体中IAI预测模型开发的现状.
主要方法:
- 在多个数据库 (PubMed,Embase,Web of Science等) 进行了全面的文献搜索. 在2025年2月之前.
- 两位研究人员独立选研究,提取数据,并使用PROBAST工具评估偏差风险和适用性.
- 包括的研究被分析为其预测性表现和验证方法.
主要成果:
- 包括22项涉及9127名患者的研究,其中的模型显示出良好的预测性能 (AUC 0.7020.987).
- 验证方法各不相同,包括内部,外部和组合方法.
- 发现的常见预测因素包括手术持续时间,糖尿病,血清白蛋白,排水保留时间和患者年龄.
结论:
- 在消化系统瘤患者中术后IAI的预测模型仍在开发中.
- 根据PROBAST的评估,所有审查的研究都表现出高偏差风险.
- 未来的研究应该强调大规模的,多中心的外部验证,并坚持报告指南,如PROBAST强大的临床应用.
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