利用数字健康干预措施来解决抑郁症的异质性:系统性审查
Ghufran Alsalloum1, Sarah Dalibalta2, Yacine Hadijat3
1Department of Bioscience and Bioengineering, College of Engineering, American University of Sharjah, Sharjah, United Arab Emirates.
Frontiers in digital health
|December 4, 2025
概括
个性化的数字健康工具通过适应个人的需求,在治疗抑郁症方面表现有前途. 这些干预措施可以改善情绪预测并减少症状,为心理健康护理提供了一条新的途径.
科学领域:
- 数字健康数字健康
- 心理健康技术 心理健康技术
- 精准医学是一门精准的医学.
背景情况:
- 抑郁症影响全球超过2.29亿人,导致严重的残疾和死亡率.
- 目前的治疗方法通常由于抑郁症的异质性而失败,导致试错护理.
- 在心理健康方面,对个性化策略的需求非常大.
研究的目的:
- 审查最近关于抑郁症个性化数字健康干预措施的文献.
- 检查这些技术如何解决抑郁症在症状,生物学和治疗反应方面的异质性.
- 综合关于数字健康对个性化抑郁症护理的有效性和局限性的发现.
主要方法:
- 在Scopus,IEEE Xplore,ClinicalTrials.gov.gov中进行系统的文献搜索 (2020年1月至2025年9月).
- 包括的研究重点是针对抑郁症异质性的个性化数字健康.
- 排除了缺乏个性化或适应性特征的通用数字健康工具;使用叙事合成.
主要成果:
- 审查了29篇出版物 (20篇研究,9篇试验),参与者超过5000人.
- 机器学习模型提高了25%的情绪预测;适应性干预显示了中等到大效果大小 (d=0.50-0.87).
- 数字疗法改善了持续的福祉,执行功能和动机,但研究存在局限性 (样本小,偏见).
结论:
- 数字心理健康为抑郁症的变化提供了个性化的干预措施.
- 证据支持增强预测,参与和结果.
- 实施需要标准化措施,股权验证和表型集成.
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