完善了吸术前诊断的精细化
Giri Prarthana1, Veeran Veeravarmal1, Sambanthan Thiruneelakandan2
1Department of Oral and Maxillofacial Pathology and Oral Microbiology, Government Dental College and Hospital, Chidambaram, Cuddalore District, Affiliated to the Tamil Nadu Dr. M.G.R. Medical University, Tamil Nadu, India.
Journal of cytology
|December 4, 2025
概括
囊性吸管的离心显著改善了对口腔病变的上皮细胞检测. 对于准确的手术前诊断,建议在离心涂抹上的帕帕尼科拉 (PAP) 染色.
科学领域:
- 口腔和面病理学 口腔和面病理学
- 细胞病理学 细胞病理学
- 诊断细胞学 诊断细胞学
背景情况:
- 口腔和大面部区域的骨内病变通常以囊性病理或带有囊性变化的瘤的形式呈现.
- 临床和放射特征的重叠使得这些病变在诊断上具有挑战性.
- 精细针吸入细胞学是一种至关重要的初步诊断工具,需要在手术前诊断和治疗规划中识别上皮细胞.
研究的目的:
- 评估涂抹制备技术 (带离心或不带离心) 的有效性,以检测骨内囊性吸收物中的上皮细胞.
- 为了比较血素和 (H&E) 和帕帕尼科劳 (PAP) 染料在识别上皮细胞方面的有效性.
- 评估细胞学和组织病理学诊断之间的一致性.
主要方法:
- 从15个临床诊断的口腔囊性病变中收集了志愿者.
- 每个病例准备了四个涂抹:两个来自非离心流体和两个来自离心流体.
- 涂抹被染色H&E和PAP染色,并评估了上皮细胞的存在.
主要成果:
- 在用离心机和不用离心机准备的涂抹中确定了上皮细胞.
- 离心术后制备的涂抹在所有15例病例中都显示了上皮细胞.
- 与非离心涂抹相比,离心涂抹中的上皮细胞存在率显著更高 (P ≤ 0.001),无论使用哪种染料.
结论:
- 囊性液体离心后的涂抹制备提高了上皮细胞检测.
- 离心涂抹上的帕帕尼科劳 (PAP) 染色是识别口腔囊性病变中的上皮细胞的最具代表性的方法.
- 改进的细胞学分析有助于准确的手术前诊断和治疗计划.
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