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一个系统的审查:通过微生物组调节对食物过敏的多的影响
Tekan Singh Rana1, Rishipal Rastrapal Bansode1, Jenny Pakhrin Rana2
1Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, Kannapolis, NC, United States.
Frontiers in microbiology
|December 4, 2025
概括
聚醇可以调节肠道微生物,帮助减少蛋和牛奶等食物过敏. 需要更多的研究来了解特定的多效应和微生物组模式,以更好地管理过敏.
科学领域:
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 食物过敏是一个日益严重的全球健康问题.
- 多,微生物和食物过敏是相互关联的,但对食物过敏中多诱导的微生物组调节的研究是有限的.
- 缺乏关于多如何影响微生物组来对抗食物过敏的既定模式.
研究的目的:
- 通过调节肠道微生物群来审查和总结当前对多如何影响食物过敏的理解.
- 为了确定与食物过敏的多干预相关的潜在微生物组调制模式.
主要方法:
- 在Scopus,PubMed,ScienceDirect和Web of Science数据库中进行系统搜索.
- 包括体内和体外研究,评估偏差风险和方法质量.
- 关于人口特征和实验细节的提取数据的叙述综合.
主要成果:
- 研究的常见食物过敏包括蛋 (54%),牛奶 (23%),大豆 (15%) 和 (8%).
- 研究了各种多,如可可,素-3-O-葡萄糖化物 (C3G) 和绿茶多 (GTP).
- 聚醇改变了肠道微生物的组成,减少了像乳酸菌这样的有益细菌,增加了像Prevotella这样的潜在有害细菌,从而减轻了食物过敏.
结论:
- 聚类型,食物过敏原,动物模型和微生物组分析技术的变化导致了不同的结果.
- 未来的研究应该专注于个体食物过敏,采用更高的分类学分辨率技术,如枪甲基因组学,并整合代谢学以提高可靠性.
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