[乙酸性食道炎的诊断和治疗]
Josealberto Sebastiano Arenas-Martínez1, Jennifer L Horsley-Silva1, Marcelo F Vela1
1División de Gastroenterología y Hepatología, Mayo Clinic Arizona. Estados Unidos. División de Gastroenterología y Hepatología Mayo Clinic Arizona Estados Unidos.
Acta gastroenterologica Latinoamericana
|December 4, 2025
概括
性食道炎 (EoE) 是一种日益严重的慢性食道疾病. 本综述强调了当前的诊断和治疗策略,包括新的生物药物,以改善患者管理.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 过敏 过敏是一种过敏.
背景情况:
- 性食道炎 (EoE) 是一种慢性,2型免疫媒介食道疾病.
- 越来越多的发病率和患病率使得EoE成为食障碍和阻塞的常见原因.
- 食物过敏原是这种炎症状况的主要触发因素.
研究的目的:
- 提供当前EoE诊断和治疗的叙述性回顾.
- 强调与拉丁美洲相关的临床应用.
- 总结一下关于管理这种慢性食道疾病的证据.
主要方法:
- 进行了截至2025年5月的叙事文献综述.
- 搜索了PubMed和其他补充数据库.
- 包括关于EoE诊断和管理的原始研究,评论,指导方针和共识声明.
主要成果:
- 诊断整合了临床,内镜和组织学发现,使用EREFS和EoEHSS等得分.
- 第一线治疗包括PPI,局部皮质类固醇和消除饮食.
- 生物药物 (例如,dupilumab) 和内镜扩张为耐火或纤维肌性EoE提供了先进的选择.
结论:
- 这需要早期诊断和全面管理.
- 挑战包括药物可用性,非侵入性生物标志物和具有成本效益的监测.
- 未来的研究应该解决这些关键领域,以改善 EoE 护理.
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