[在家护理动脉样硬化监测系统的开发与心脚血管指数集成]
Xichun Xu1, Kexin Chen1, Jinqi Lin1
1School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, 518000.
概括
这项研究引入了一种新的家庭护理系统,通过测量心脚血管指数 (CAVI) 和脚臂指数 (ABI) 来监测动脉样硬化. 该设备提供可靠的查,克服了传统方法的局限性,易受血压干扰的影响.
科学领域:
- 生物医学工程 生物医学工程
- 心血管健康 心血管健康
- 医疗器械开发 医疗器械开发
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因.
- 动脉样硬化是心血管疾病的主要病理因素,需要有效的早期查.
- 现有的检测方法,如脉冲波速度 (PWV),遭受血压干扰和操作复杂性.
研究的目的:
- 开发一个集成的家庭护理动脉样硬化监测系统.
- 为了能够同时测量心脚血管指数 (CAVI) 和脚腕指数 (ABI).
- 克服当前设备的局限性,特别是对血压波动的敏感性和专业操作的需要.
主要方法:
- 硬件集成:灵活的银离子电极,剪贴式手套,心脏声传感器,分级通胀血压模块.
- 信号采集:用于同步多信号处理的STM32F405微控制器.
- 软件开发:用于驱动程序的MDK,用于用户界面的Visual Studio (数据采集,显示,存储).
- 算法方法:用于物理信号特征提取的Pan-Tompkins算法,用于计算CAVI和ABI.
主要成果:
- 系统性能:心电图噪声<20μV,常态排斥比为95dB,血压误差<2mmHg.
- 临床验证:CAVI与PWV显示强烈的正相关性 (r=0.85,P<0.001) 并较少受到血压的影响.
- 趋势分析:动脉样硬化指标 (CAVI,PWV,ABI) 随着年龄和高血压和高脂血症等危险因素的增加而增加.
结论:
- 开发的家庭护理系统为非临床环境中的动脉样硬化查提供了可靠的工具.
- 它克服了传统设备的缺点,提供了易于使用和减少血压干扰.
- 该系统对动脉样硬化的早期检测和临床诊断支持具有重要价值.
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