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Updated: Jan 9, 2026

Light-sheet Fluorescence Microscopy to Capture 4-Dimensional Images of the Effects of Modulating Shear Stress on the Developing Zebrafish Heart
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Published on: August 10, 2018

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单向剪切应力操作的NOTCH/CXCR4分子开关控制半月膜成熟和原分层

Charles R Dai1, Duc H Pham1,2, G Janani1

  • 1The Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY (C.R.D., D.H.P., G.J., B.L., J.T.B.).

Arteriosclerosis, thrombosis, and vascular biology
|December 4, 2025
PubMed
概括

剪切应激激活内心细胞中的NOTCH1/CXCR4分子开关,通过抑制生长和促进组织重塑来调节胎儿心脏膜成熟. 这确定了一个血液动力学提示控制门发育.

关键词:
生物物理学的生物物理学.原蛋白是一种原蛋白.细胞外矩阵是细胞外矩阵.血液动力学 血液动力学形态发生 (morphogenesis) 是一种形态的产生.

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