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Updated: Jan 9, 2026

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice
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内皮ADAR1缺陷诱导NOCT-IRF7轴在肺高血压中的作用

Chen-Shan Chen Woodcock1,2,3, Giovanni Maroli4,5, Hyunbum Kim6

  • 1Center for Pulmonary Vascular Biology and Medicine, Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute (C.C.W., Y.Y.T., Y.T., S.O., R.H., S.J., B.W., Y.A.A., T.V.K., S.Y.C.).

Circulation research
|December 4, 2025
PubMed
概括

在肺高血压 (PH) 中减少ADAR1RNA编辑导致NOCT表达增加,触发免疫信号和细胞死亡. 针对ADAR1-NOCT通路可能提供新的PH疗法.

关键词:
灭症 (apoptosis) 是一种死亡的过程.它们是内皮细胞.干扰子干扰子干扰子在夜晚的夜晚.肺动脉中的肺动脉.

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