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初级皮肤淋巴瘤的新兴流行病学趋势:基于人口的分析

Yanwu Lu¹, Lian Zhang¹, Xiaoqi Ying¹

¹Dermatology Medical Cosmetology Center, Ningbo Hospital of Traditional Chinese Medicine, Zhejiang, China.

Clinical and experimental dermatology

|December 4, 2025

概括

皮肤淋巴瘤 (CLs) 发病率在过去十年中在美国下降,皮肤T细胞淋巴瘤 (CTCLs) 和皮肤B细胞淋巴瘤 (CBCLs) 显著下降. 幸存率仍然很高,但差异仍然存在,需要有针对性的研究.

科学领域:

在瘤学瘤学.
流行病学流行病学
皮肤病学皮肤病学

背景情况:

初级皮肤淋巴瘤 (CLs),包括CTCL和CBCL,是一种罕见的非霍奇金淋巴瘤,具有独特的流行病学特征.
过去十年来LC发病率的趋势没有得到充分的证据.

研究的目的:

分析美国CL总体和特定发病率的变化.
检查不同性别,年龄组和种族背景的这些变化.

主要方法:

利用了从2010年至2021年间诊断的13,126例CL病例的数据,来自监测,流行病学和最终结果计划.
根据年龄调整的发病率 (IR),五年相对存活率和年均百分比变化.

主要成果:

总的来说,每10万人年中CLs的IR为11.9 (CTCLs:8.8;CBCLs:3.1).
CTCL和CBCL的发病率每年分别下降了2.8%和4.9% (2014-2021年).
五年相对存活率为CTCLs的89.3%和CBCLs的91.5%.

结论:

在过去的十年中,CL的发病率在人口群体中呈现出不同的下降模式.
持续的发病率和生存率差异凸显了针对性研究和干预措施的必要性,以解决不平等问题.

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