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Updated: May 6, 2026

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在眼睛毒性研究中超越眼睛变化:对眼外视觉通路的采样和评估的实际考虑,以及常见的发现

Typhaine Lejeune1, Helen Booler2, Joan Wicks3

  • 1Charles River Laboratories Montreal ULC, Senneville, Quebec, Canada.

Toxicologic pathology
|December 4, 2025
PubMed
概括

这项研究为在临床前眼部药物安全性研究中评估眼外视觉通路毒性的指南. 它强调在眼部给药后检查中枢神经系统是否有药物诱导的毒性.

关键词:
大脑采样采样状腺节 状腺节基因治疗的基因疗法非人类灵长类的灵长类.眼睛毒性 眼睛毒性视觉路径 视觉路径 视觉路径

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Accessory Structures of the Eye01:17

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Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
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