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Updated: Jan 9, 2026

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集群级分析以估计集群随机试验中的风险差异与混个体级共变量:一个模拟研究

Jules Antoine Pereira Macedo1, Bruno Giraudeau1,2,

  • 1Université de Tours, Nantes Université, INSERM, SPHERE U1246, Tours, France.

Statistics in medicine
|December 4, 2025
PubMed
概括

集群随机试验 (CRT) 分析需要仔细考虑个人层面的混因素. 定向最大概率估计 (TMLE) 提供了无偏见的风险差异估计,特别是在少数集群的情况下,优于其他方法.

关键词:
二元结果的二元结果.集群随机试验是指一个集群随机试验.在集群层面进行分析.通过g-计算计算.风险差异的风险差异是什么有针对性的最大概率估计.

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