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血管造影与基于血管的分数流相比,用于评估内脊椎关动脉狭窄

Yongsheng Liu¹, Guiwen Shao², Yuxiang Liu²

¹Department of Interventional Neuroradiology, First Affiliated Hospital of Dalian Medical University, Dalian, China. liuyongsheng_dl@163.com.

European radiology

|December 4, 2025

概括

基于血管的分流 (Angio-FF) 是一种优越的诊断工具,用于识别症状的内脊柱动脉狭窄症 (IVBS),而不是单独的狭窄程度. 这种方法为个性化治疗策略提供了改进的血液动力学风险分层.

科学领域:

神经学神经学
心脏病学心脏病学
医疗成像医学成像

背景情况:

内脊动脉狭窄 (IVBS) 是中风的一个重要原因.
准确识别症状IVBS对于有效治疗和预防中风至关重要.
目前的诊断方法,主要是基于狭窄 (DS) 的程度,可能无法完全捕捉这些病变的血液动力学意义.

研究的目的:

评估基于血管的分流流 (Angio-FF) 在识别症状IVBS的诊断性能.
在诊断准确性方面,将Angio-FF与狭窄度 (DS) 进行比较.
评估Angio-FF在各种损伤亚组中的实用性.

主要方法:

对120名单边IVBS (40-90%狭窄) 患者的回顾性分析.
使用专用软件计算Angio-FF;通过数字减去血管学评估DS.
在Angio-FF和DS之间比较的诊断准确度,灵敏度,特异性,PPV,NPV和AUC.

主要成果:

在识别症状性IVBS时,Angio-FF表现出优于DS的诊断性能 (AUC:0.847与0.640,p<0.001).
最佳的Angio-FF切线为0.74,灵敏度为71.4%,特异性为86.1%,精度为75.8%.
血管-FF在各种病变亚组 (长度,位置,DS) 中表现一致.

结论:

在诊断症状性IVBS时,Angio-FF显著优于DS.
在IVBS中,Angio-FF作为血液动力学风险分层的可靠工具.
这种技术可以为IVBS患者提供更个性化的治疗策略.

关键词:

血管学血管学血管学分流流量流量流量流量流量流量流量血液动力学血液动力学内狭窄症内狭窄症脊椎大关动脉脊椎大关动脉

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