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Updated: Jan 9, 2026

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介素-1/托尔类受体信号传递增强了巨细胞嗅觉受体2驱动动动脉硬化

Lujun Zhang1, Jili Fu2, Zicheng Hu3

  • 1Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China; Precision Medicine Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Municipality Clinical Research Center for Geriatrics and Gerontology, Chongqing, China.

Cell reports
|December 4, 2025
PubMed
概括

介质素-1受体1型 (IL-1R1) /通道状受体 (TLR) 信号传导通过阻断巨细胞中嗅觉受体6A2 (OR6A2) 内化促进动脉样硬化. 这种机制增强了NLRP3炎症酶的激活,有助于疾病的进展.

关键词:
CP:免疫学 免疫学CP:代谢过程中的代谢.在IL-1R中,IL-1R是最常见的.在OR6A2中,它是OR6A2.这是一个TLR.在TRAF6中,动脉样硬化 动脉样硬化一些炎症一些炎症这是一种炎症炎症炎症炎症.巨细胞是一个巨细胞.这是一种β-arrestin-2的组合.

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