Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Proofreading01:31

Proofreading

8.6K
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase...
8.6K
Proofreading01:43

Proofreading

59.7K
Overview
59.7K
Clot Retraction and Fibrinolysis01:16

Clot Retraction and Fibrinolysis

8.3K
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
8.3K
Mismatch Repair01:36

Mismatch Repair

43.5K
Overview
43.5K
Mismatch Repair01:20

Mismatch Repair

6.2K
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
6.2K
Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

7.8K
Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
7.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Urinary and Plasma KIM-1 in Chronic Kidney Disease: Prognostic Insights and Remaining Questions.

American journal of nephrology·2025
Same author

Erratum.

International archives of allergy and immunology·2025
Same author

Retraction Statement.

Oncology·2025
Same author

Erratum.

Neuro-degenerative diseases·2025
Same author

Erratum.

Nephron·2025
Same author

Erratum.

Digestion·2025
Same journal

Integrating Psychosocial Factors into Artificial Intelligence Models for Predicting Addiction Treatment Outcomes: A Systematic Review.

European addiction research·2026
Same journal

Sweet flavors and the addictive potential of e-cigarettes: A systematic narrative review.

European addiction research·2026
Same journal

FDA Approves Reduced Drinking Endpoints for Alcohol Trials: A New Road for Alcohol Treatment?

European addiction research·2026
Same journal

Patterns and mood effects of concomitant polydrug use of ecstasy and alcohol in Dutch and British electronic dance event visitors: an EMA study.

European addiction research·2026
Same journal

Gambling severity and the use of general health care and social services: a nationwide population survey of service use and associated factors.

European addiction research·2026
Same journal

Lessons Learned from Implementing a Centrally Organized, Cross-Sectoral, Patient-Centered Treatment Coordination System for Hazardous Substance Use and Substance Use Disorders: The randomized controlled ASSIST Study.

European addiction research·2026
查看所有相关文章

相关实验视频

Updated: Jan 9, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
03:25

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

1.3K

这就是Erratum Erratum.

    European addiction research
    |December 4, 2025
    PubMed
    概括
    此摘要是机器生成的。

    这项研究发现,非处方使用阿片类激素药物与非致命的过量服用有关. 十年来减少的监测并没有阻止这种关联,强调了阿片类药物治疗中的持续风险.

    科学领域:

    • 成 药物 药物 药物 药物
    • 公共卫生 公共卫生
    • 药理学 药理学是指药理学的学科.

    背景情况:

    • 无处方使用阿片类激素药物 (OAMs) 是一个令人担忧的问题.
    • 了解非处方OAM使用与非致命过量服用之间的关联对于公共卫生至关重要.
    • 在过去的十年中,对OAM的监测政策已经减少.

    研究的目的:

    • 调查OAMs非处方使用与非致命过量服用之间的关联.
    • 分析十年来该协会的趋势,减少监测.

    主要方法:

    • 重复的横截面研究设计.
    • 利用跨越十年的数据.
    • 检查了非处方OAM使用和非致命的过量事件之间的关联.

    主要成果:

    • 非处方使用OAM与非致命的过量服用有关.
    • 尽管监测减少,但这种关联在整个十年内一直存在.

    结论:

    • 这些发现强调了与非处方OAM使用相关的持续风险.
    • 政策影响表明需要策略来减轻非处方OAM使用和过量服用的风险.

    更多相关视频

    Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
    09:41

    Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

    Published on: June 17, 2014

    12.5K
    Surgical Correction for Pediatric Epiblepharon and Trichiasis
    03:59

    Surgical Correction for Pediatric Epiblepharon and Trichiasis

    Published on: July 8, 2025

    460

    相关实验视频

    Last Updated: Jan 9, 2026

    Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
    03:25

    Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

    Published on: June 16, 2022

    1.3K
    Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
    09:41

    Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

    Published on: June 17, 2014

    12.5K
    Surgical Correction for Pediatric Epiblepharon and Trichiasis
    03:59

    Surgical Correction for Pediatric Epiblepharon and Trichiasis

    Published on: July 8, 2025

    460
  • 对有效的监测和减少危害的战略进行进一步的研究是有必要的.