在Bos taurus哺乳牛肉牛的基于孕激素的TAI协议中,雌激醇 Ester是不可缺少的
Alinne Machado Petrarca Léo1, Fabiane Pereira de Moraes1, Monique Tomazele Rovani2
1Federal University of Pelotas, FiBRA research group, Faculty of Veterinary Medicine, Pelotas, RS, Brazil.
Animal reproduction science
|December 4, 2025
概括
在肉牛的定时人工授精 (TAI) 方案中用GnRH取代雌激素并没有影响卵泡大小,雌激素表达或怀孕率. 这一发现支持GnRH作为TAI协议中可行的替代品.
科学领域:
- 畜牧业生殖内分泌学 在畜牧业生殖内分泌学
- 人工授精技术的人工授精技术
- 牛的繁殖和生育能力.
背景情况:
- 南美洲的定时人工授精 (TAI) 协议通常使用孕激素 (P4) 和雌激素 (E2).
- 对雌醇使用的限制需要探索替代激素干预措施.
- 淋巴激素释放激素 (GnRH) 是TAI协议中雌激素的潜在替代品.
研究的目的:
- 为了评估用GnRH替代雌激素在多胎母乳Bos taurus奶牛的TAI协议中的疗效.
- 为了比较不同激素治疗对卵泡发育,雌性表达和怀孕率的影响.
主要方法:
- 455只多母乳Bos taurus奶牛接受了涉及P4阴道器件 (IVD) 的TAI协议.
- 奶牛被分配到控制 (雌二酸),GnRH/GnRH或GnRH/雌二酸 (EC) 组.
- 激素治疗包括P4 IVD,GnRH或雌二酸/酸,克洛普醇和eCG,在D9上进行TAI.
主要成果:
- 在 D7 上最大的毛囊 (LF) 直径或黄体 (CL) 存在方面,没有观察到显著的差异.
- 在对照 (56.9%),GnRH/EC (53.1%) 和GnRH/GnRH (53.6%) 组中,怀孕率相似.
- 在TAI之前的雌激素率也没有显示治疗组之间的显著差异.
结论:
- 在哺乳肉牛的TAI协议中用GnRH取代雌激素不会对最大的卵泡直径,雌激素表达或怀孕率产生负面影响.
- 在TAI协议中,GnRH是雌激素的有效替代品,由于雌激素使用限制,它提供了灵活性.
- 这项研究验证了GnRH作为Bos taurus牛的TAI同步策略中合适的组成部分.
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