职业压力暴露与消防员白质完整性改变之间的关联
Hyeonseok Jeong1, Yejin Kim2, Yoonji Joo1
1Ewha Brain Institute, Ewha Womans University, Seoul, South Korea.
Journal of affective disorders
|December 4, 2025
概括
消防员表现出与工作压力相关的白质 (WM) 变化,影响睡眠和身体健康. 这突出了从职业压力到该组不良临床结果的神经生物学途径.
科学领域:
- 神经成像是一种神经成像.
- 职业健康 职业健康 职业健康
- 神经科学是一个神经科学.
背景情况:
- 消防员因创伤和轮班工作而面临慢性压力,导致睡眠障碍和体质症状.
- 了解消防员的白质 (WM) 完整性至关重要,但仍未得到充分探索.
- 这项研究调查了WM微观结构变化及其与消防员的临床联系.
研究的目的:
- 为了研究消防员的白质 (WM) 微观结构变化.
- 探索这些变化与职业压力之间的联系.
- 为了检查WM变化和与压力相关的症状,如睡眠障碍和体质投诉之间的关系.
主要方法:
- 扩散张力成像 (DTI) 用于评估94名消防员和98名对照者的白质 (WM) 完整性.
- 基于通道的空间统计 (TBSS) 分析了扩散指数的群体差异.
- 标准化临床评估测量了累积的职责暴露和与压力相关的症状.
主要成果:
- 与对照人群相比,消防员在大脑的广泛区域显示了轴向扩散率 (AD) 和平均扩散率 (MD) 的增加.
- 较高的累积应急任务暴露与消防员中AD和MD的增加相关.
- 增加的AD显著与睡眠质量降低和更严重的身体症状有关.
结论:
- 消防员的慢性职业压力与显著的白质 (WM) 微观结构变化有关.
- 这些WM变化与睡眠质量下降和身体症状增加相关.
- 研究结果表明,从职业压力到临床结果的神经生物学途径,强调了早期干预的必要性.
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