血小板生产的实践:一个北欧视角 (2018-2022)
Aseel Alshamari1, Tynngård Nahreen2,3, Jarkko Ihalainen4
1Department of Clinical Immunology and Transfusion Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Vox sanguinis
|December 4, 2025
概括
北欧的血小板度产量各不相同. 实施降低病原体或细菌培养查并储存7天可以提高区域血液供应的弹性和安全性.
科学领域:
- 输血医学 输血医学
- 血液学 血液学 血液学
- 公共卫生 公共卫生
背景情况:
- 北欧地区,拥有超过2750万人口,在丹麦,芬兰,冰岛,挪威和瑞典拥有多样化的血液服务管理.
- 了解目前的血小板缩物 (PC) 生产方法和产能对于区域效率和准备能力至关重要.
研究的目的:
- 在2018年至2022年期间,调查和分析北欧地区的PC生产方法,安全措施和产能.
- 识别收集程序,细菌查和储存实践中的变化.
主要方法:
- 在所有生产血小板的北欧血液中心中进行了一项回顾性在线调查.
- 收集的数据涵盖了采集方法 (非与全血衍生),细菌培养查 (BCS),病原体减少 (PR),保质期和质量控制.
主要成果:
- 43个血液中心参与了调查 (83%的响应率),涵盖了芬兰,冰岛和瑞典的国家数据.
- 在2018年至2022年期间,生产了632,596个PC;大多数是全血衍生池 (77%).
- 17个中心使用了病原体减少,23个中心使用了BCS. 使用PR或BCS的保质期延长到7天,而没有PR或BCS的保质期延长到5天.
结论:
- 北欧的血小板生产和对抗细菌污染的安全措施存在显著差异.
- 协调实践,包括采用PR或BCS延长7天的保质期,可以加强区域血小板供应的弹性.
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