移民时间改变了老年人药物不坚持和认知功能之间的关联
1Department of Mathematics and Statistics, College of Sciences, Old Dominion University, 4700 Elkhorn Avenue, Norfolk, VA, 23529, United States.
Research in social & administrative pharmacy : RSAP
|December 4, 2025
概括
无意不服药 (MNA) 可能表明认知能力下降,特别是在晚年抵达的移民中. 通过MNA和移民历史的早期识别可以指导对各种老年人的干预.
科学领域:
- 老年学是一门学科.
- 认知神经科学 认知神经科学
- 公共卫生 公共卫生
背景情况:
- 老龄化移民人口面临痴呆风险,由于文化/语言障碍,传统方法往往无法检测到.
- 无意的药物不服药 (MNA) 是潜在的早期,非侵入性的认知衰退标志物.
- 移民时间对MNA-认知关系的影响还未得到充分研究.
研究的目的:
- 调查非故意的药物不服药 (MNA) 作为老年人认知能力下降的标志物.
- 检查移民身份和时间如何改变MNA与认知功能之间的关联.
- 评估教育在MNA-认知关系中的保护作用.
主要方法:
- 从健康和退休研究 (2012-2016) 中分析了10854名65岁以上的参与者.
- 使用标准化潜在认知分数评估认知功能.
- 根据入境时的年龄对移民的分层和MNA,移民和教育相互作用的回归分析.
主要成果:
- 不故意的MNA,移民身份和移民时的年龄较大与较低的认知分数相关.
- 移民状况,时间和教育显著缓解了MNA-认知协会.
- 非故意的MNA对认知的影响因种族和移民子组而异,受移民时间和教育的影响.
结论:
- 非故意的MNA作为认知衰退的敏感指标,特别是在中晚成年时抵达的移民中.
- 将药物坚持和移民史纳入临床评估可以提高认知衰退的早期检测.
- 基于这些发现,可以为各种老年人群开发有针对性的干预措施.
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