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Updated: Jan 9, 2026

Discovery of Metastatic Regulators using a Rapid and Quantitative Intravital Chick Chorioallantoic Membrane Model
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Published on: February 3, 2021

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KY216-氨酸复合物捕获VASH2,以抑制NSCLC的转移

Xiao-Yu He1, Cheng-Yan Liu1, Xin-Yu Ding2

  • 1Basic Medical Research Innovation Center for Anti-Cancer Drugs, MOE and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.

Nature communications
|December 4, 2025
PubMed
概括

一种新型的微管抑制剂,KY216,通过向静脉激素-2 (VASH2) 来抑制非小细胞肺癌 (NSCLC) 转移. 这种机制涉及阻碍表皮-介质细胞过渡 (EMT) 并影响潜在治疗策略的关键分子通路.

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