甘油三和高密度脂蛋白胆固醇的比例及其与牙周炎的关联 - - 一项系统性审查
Shashikiran Shanmugasundaram1, Shaswata Karmakar2, Ramya Arangaraju3
1Department of Periodontology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India. shashi.ks@manipal.edu.
BDJ open
|December 4, 2025
概括
甘油三和高密度脂蛋白胆固醇的比率 (Ty/HDLc比率) 与牙周炎的患病率和严重程度有积极的联系. 这种可访问的生物标志物可以帮助识别患有牙周病风险的个体.
科学领域:
- 口腔健康 口腔健康
- 代谢健康 代谢健康
- 生物标志物 生物标志物
背景情况:
- 牙周健康与代谢健康密切相关.
- 肥胖,代谢综合征和糖尿病双向与牙周炎有关.
- 甘油三和高密度脂蛋白胆固醇的比率 (Ty/HDLc比率) 是代谢疾病的新型生物标志物.
研究的目的:
- 系统地审查和整合关于Ty/HDLc比率与牙周炎之间的关联的证据.
- 评估Ty/HDLc比率作为牙周炎的潜在间接风险标志物.
主要方法:
- 在PubMed,SCOPUS,Embase和Web of Science数据库中进行系统搜索.
- 包括成人和青少年的观察性研究;排除干预研究,病例报告和动物研究.
- 使用乔安娜·布里格斯研究所的批判性评估检查清单进行质量评估.
主要成果:
- 七项研究符合资格标准,样本大小从69到13,584.
- 在巴西,墨西哥,韩国和台湾的不同人群中进行了研究.
- 所有包括的研究都表明,Ty/HDLc比率与牙周炎患病率和/或严重程度之间存在一致的正相关性,偏差风险较低.
结论:
- 血清Ty/HDLc比率与牙周炎患病率有积极关联.
- Ty/HDLc比率是牙周炎的一个有希望的,实用的和成本效益的间接风险标志物.
- 未来的研究应该为牙周风险评估建立时间关系和性别特定的切线.
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