用于认知的全脑网络分布在哪里?
Matthew C Rosen1, David J Freedman2,3
1Department of Neurobiology, The University of Chicago, Chicago, IL, USA. matthew.casciola.rosen@gmail.com.
Nature reviews. Neuroscience
|December 4, 2025
概括
神经科学研究挑战了本地化大脑功能的概念. 新的发现表明认知过程在大脑中广泛分布,甚至在运动控制区域.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 计算神经科学是一种神经科学.
背景情况:
- 从历史上看,神经生理学倾向于'局部化'的大脑功能观点,将复杂的行为归因于专门的大脑区域.
- 最近在动物中进行的高通量神经记录表明了神经编码的更分散的模型,称为"一切,到处,一次".
研究的目的:
- 为了评估本地化或分布式模型是否更好地解释认知,定义为灵活行为的内部变量操纵.
- 研究动物和灵长类动物大脑中的认知变量表示的范围和分布.
主要方法:
- 对神经生理学记录技术和来自动物和灵长类动物研究的数据分析的审查.
- 对认知功能的局部与分布式编码范式进行比较分析.
主要成果:
- 认知变量在大脑中广泛表现,而不是严格局限于特定区域.
- 在参与运动控制的大脑区域发现了意想不到的显著的认知信号存在.
结论:
- 大脑的认知处理似乎比以前认为的更分散,挑战了严格局部化的模型.
- 为了了解认知过程中大脑网络的招募,需要考虑影响信号宽度的因素以及运动控制区域的作用.
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