在巴西人口中估计的脉冲波速度模型的外部验证和本地调整
Valerio Garrone Barauna1, Jeremias da Silva Leão2, Divanei Zaniqueli3
1Department of Physiological Sciences, Federal University of Espírito Santo, Vitória, ES, Brazil.
概括
在巴西人中,估计脉冲波速度 (ePWV) 的新方程改善了心血管风险评估. 这些针对特定人群的模型提供了更准确的动脉硬度估计,提高了公共卫生中的临床实用性.
科学领域:
- 心血管研究的心血管研究.
- 生物医学工程 生物医学工程
- 公共卫生 公共卫生
背景情况:
- 估计脉冲波速度 (ePWV) 是一种非侵入性心血管风险评估工具.
- 由于遗传和环境因素,现有的ePWV方程可能在像巴西人这样的不同人群中缺乏准确性.
研究的目的:
- 在巴西队列中验证欧洲ePWV方程.
- 为巴西人开发新的,特定于人口的ePWV估计模型.
主要方法:
- 分析了来自2122名巴西成年人的数据,测量了带-大腿脉冲波速 (cfPWV),年龄,平均动脉压 (MAP) 和性别.
- 开发了线性回归模型,并使用RMSE和R2评估了性能.
- 使用Bland-Altman分析评估估计和测量cfPWV之间的一致性.
主要成果:
- 新开发的巴西ePWV方程的表现优于现有的欧洲模型.
- 最好的模型实现了0.744的RMSE,优于ASCG模型 (RMSE:0.879).
- 包括性别提高了准确性;布兰德-阿尔特曼分析显示了更窄的协议边界.
结论:
- 特定人口的ePWV方程提高了巴西人的动脉硬度估计准确度.
- 改进的精度允许使用低成本工具更好地分层心血管风险.
- 在不同人群中验证风险评估工具对于临床实用性至关重要.
相关概念视频
01:23Assessment of blood pressure in brachial artery(two-step method)
1.4K
Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
1.4K
01:15Assessment of blood pressure in brachial artery(one-step method)
1.1K
This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
Prepare for the Procedure:
1.1K
01:19Assessing Blood pressure using a doppler ultrasound
2.3K
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
2.3K
01:25Assessment of apical radial pulse
1.2K
Apical-Radial (A-R) Pulse Assessment
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
1.2K
01:11Assessment of radial pulse
1.3K
Assessment of Radial Pulse
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
1.3K
01:17Measurement of Blood Pressure
2.6K
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
2.6K