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Updated: Jan 9, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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Published on: April 3, 2014

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沿着Tpt1-催化酸从核酸转移到NAD的水晶结构和快照

Chulei Cao1, Jie Yang1, Weizhen Zhang1,2

  • 1State Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.

Nature communications
|December 4, 2025
PubMed
概括

这项研究揭示了Tpt1 (TkoTpt1) 的晶体结构,捕获了tRNA成熟和核酸修饰中的关键中间体. 这些发现重申了TPT1家族蛋白质在酸盐转移中的催化机制.

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