在一般人群中,听力损失与心血管和死亡风险的关联
Omar Hahad1,2, Julia Döge3, Katharina Bahr-Hamm3
1Department of Cardiology - Cardiology I, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstraße 1, 55131, Mainz, Germany. omar.hahad@unimedizin-mainz.de.
Scientific reports
|December 4, 2025
概括
听力损失影响全球许多人,并与心血管问题有关. 这项研究表明,听力损失可能表明潜在的血管问题,特别是糖尿病,而不是直接导致心脏病或死亡.
科学领域:
- 流行病学 流行病学
- 听力学 听力学是指听力学.
- 心脏病学 心脏病学
背景情况:
- 听力损失影响全球超过15亿人,导致社会隔离和认知能力下降.
- 新出现的证据表明,听力障碍和心血管疾病 (CVD) 之间存在相关性.
- 有限的综合流行病学研究存在于听力损失和心血管疾病之间的关联.
研究的目的:
- 研究听力损失,心血管疾病,风险因素和全因死亡率之间的关系.
- 为了分析基于人口的古堡健康研究队列的数据.
- 确定听力损失是否是心血管疾病或死亡率的独立预测因素.
主要方法:
- 利用了古登堡健康研究中15,010名参与者 (35-74岁) 的数据.
- 进行了听力测量评估和临床评估.
- 应用后勤回归和考克斯比例危险模型,对混因素进行调整.
主要成果:
- 在8886名具有完整听力数据的参与者中,有35.1%的人有某种程度的听力损失.
- 原始分析显示了听力损失和心血管疾病/风险因素之间的关联,但在调整后,这些失去了意义.
- 听力损失和糖尿病之间仍然存在显著的关联 (aOR 1.24,95% CI 1.01-1.51).
- 在未调整的模型中,听力损失与较高的死亡率有关,但在完全调整后,这种情况消失了.
结论:
- 听力损失可能是系统性血管功能障碍的早期指标,特别是在糖尿病患者中.
- 在这个群体中,听力损失不是心血管疾病或死亡率的独立预测因素.
- 需要进一步的研究来探索将听觉健康纳入心血管评估,以改善早期检测和预防.
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