甲状腺癌妇女体外受精的结果:一个病例报告
Wenping Wang1, Jing Yang2, Ping Liao2
1Center for Reproductive Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, People's Republic of China. 3587993@qq.com.
BMC pregnancy and childbirth
|December 4, 2025
概括
这项案例研究表明,患有甲状腺癌的不孕女性可以成功接受体外受精 (IVF) 并获得积极的妊娠结果. 甲状腺癌的治疗可以推迟到辅助生殖技术 (ART) 程序之后.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 在瘤学瘤学.
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 在患有甲状腺癌的生育年龄妇女怀孕带来管理挑战.
- 甲状腺切除术对怀孕结果的影响受到争论.
- 关于甲状腺癌不育妇女的辅助生殖技术 (ART) 的数据有限.
研究的目的:
- 在患有乳头甲状腺癌 (PTC) 的不孕女性中成功进行体外受精 (IVF) 的案例.
- 评估ART在未经治疗的甲状腺癌患者中的安全性和有效性.
- 在接受试管婴儿的PTC患者中评估怀孕和新生儿后果.
主要方法:
- 一名36岁的不育妇女被诊断为PTC,接受了受控卵巢刺激 (COS),使用灵活的对抗剂协议.
- 进行了传统的试管婴儿和冷胚胎移植 (FET).
- 甲状腺激素水平和部超声波受到密切监测,并且调整了勒沃西的剂量以维持目标TSH水平.
- 人工子宫内膜制剂被用于FET.
主要成果:
- 采集了13个卵细胞,并获得了5个活跃的胚胎.
- 在移植4CB胚胎囊后,获得了临床怀孕.
- 一个健康的男婴在怀孕39周通过剖腹产分娩,没有产妇或新生儿并发症.
- 乳头甲状腺癌在产后6个月内保持稳定.
结论:
- 甲状腺癌手术可以推迟到ART程序和怀孕完成后.
- 在这种情况下,乳头甲状腺癌并没有对试管婴儿,产科或新生儿结果产生不利影响.
- 对于患有甲状腺癌的不育妇女来说,ART是一种可行的选择,在仔细监测甲状腺功能的情况下.
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