吸烟对术后疼痛和恶心以及吐的影响
Hana Khalili1,2, Faridah Ihmoud1, Hammam Abdelrazeq1,2
1Department of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, Nablus, 44839, Palestine.
目前的吸烟状态不能独立预测早期术后疼痛 (POP) 或术后恶心和吐 (PONV). 需要进一步的研究来确定这些常见的手术并发症的可靠预测因素.
科学领域:
- 麻醉学和外科手术期间的医学.
- 公共卫生 公共卫生
- 临床研究 临床研究
背景情况:
- 手术后的疼痛 (POP) 和手术后的恶心和吐 (PONV) 是常见的,令人痛苦的手术并发症.
- 关于吸烟作为影响POP和PONV的可修改因素的证据是不一致的,特别是来自低收入和中等收入国家 (LMICs).
研究的目的:
- 调查当前吸烟状态是否独立地预测LMIC环境中的早期POP和PONV.
- 分析吸烟与POP和PONV的存在和严重程度之间的联系.
主要方法:
- 在巴勒斯坦的两个三级转诊医院进行了前性观察性研究.
- 包括200名在全身麻醉下接受选择性手术的成年患者.
- 自我报告的吸烟状态,结果 (恶心,吐,疼痛) 通过视觉模拟尺度 (VAS) 和逻辑回归分析在手术后24小时进行评估.
主要成果:
- 原始率显示吸烟者和非吸烟者之间对恶心,吐和疼痛的差异.
- 在对多种因素进行调整后,目前的吸烟状态与手术后恶心 (aOR 1.57),吐 (aOR 1.13) 或疼痛 (aOR 0.98) 没有显著相关.
- 在吸烟状态和这些结果的严重程度之间没有发现显著的关联.
结论:
- 目前的吸烟状况不是LMIC队列中早期POP或PONV的独立预测因素.
- 周围手术风险分层应该包含经过验证的预测因素,而不仅仅是吸烟状态.
- 需要进一步的大规模,标准化的多中心研究,以更精确地量化吸烟暴露.
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