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Updated: Jan 9, 2026

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通过驱动ATM-TBK1酸化信号通路来调解抗病毒效应

Hongyan Sui1, Rosana Wiscovitch-Russo1, Silvia Cachaco1,2

  • 1Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory, Frederick, MD, United States.

Frontiers in immunology
|December 5, 2025
PubMed
概括

(Mn) 激活了细胞质中阿塔克西亚-泰朗基切塔西亚突变 (ATM) 激酶,导致TBK1酸化. 这种途径增强了抗病毒细胞因子的产生,并抑制了HIV复制,这表明Mn是潜在的抗病毒疗法.

关键词:
这是一个ATMATMATM.在TBK1中,抗病毒免疫力抗病毒免疫力酸是一种酸.酸化的方法是:光化.

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