四分之一世纪的医疗保健合成数据:通过结构性主题建模揭示趋势
Billy Ogwel1,2, Vincent H Mzazi2, Alex O Awuor1
1Center for Global Health Research (KEMRI-CGHR), Kenya Medical Research Institute, Kisumu, Kenya.
Digital health
|December 5, 2025
概括
医疗保健中的合成数据研究正在迅速增长,来自亚洲的贡献越来越多,并转向疾病建模和公共卫生主题. 实现其全部潜力需要合作和偏见缓解.
科学领域:
- 医疗保健研究的研究.
- 数据科学是数据科学.
- 生物医学信息学是生物医学信息学.
背景情况:
- 合成数据在医疗保健中越来越多地被用于克服数据限制.
- 了解研究环境对于指导未来发展至关重要.
研究的目的:
- 从2000年到2024年,系统地绘制医疗保健中合成数据研究的演变图.
- 确定关键的研究主题,随着时间的推移,以及地理分布的趋势.
主要方法:
- 结构主题建模 (STM) 用关键词"合成数据"",人工数据"或"模拟数据"应用于7533篇PubMed文章 (2000-2024年).
- 分析将出版年和大陆作为共同变量纳入分析.
- 通过堆叠区域图表和网络分析,分析了主题的趋势和相关性.
主要成果:
- 观察到出版物增加了20倍,亚洲贡献显著增加 (4.7%至24.1%).
- 主要研究主题包括计算和统计方法 (34.3%),基因组学和分子生物学 (23.9%),生物医学成像和信号处理 (21.1%),以及合成数据应用 (20.7%).
- "合成数据生成"和"疾病建模和公共卫生"等主题显示出实质性的增长,而"贝叶斯建模"和"统计偏见和缺失数据"则下降.
结论:
- 医疗保健合成数据研究正在全球范围内扩大,主题重点不断变化.
- 未来的进步取决于跨学科的合作,解决偏见,促进公平的伙伴关系.
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