石家庄对功能性消化不良的影响:系统性审查和元分析
Hanbum Bae1, Jinsung Kim2, Soyeon Kim1,3
1Department of Korean Medicine, The Graduate School of Pusan National University, Yangsan, Republic of Korea.
石家庄 (SG) 在治疗功能性消化不良 (FD) 方面表现有前途,效果更好,副作用比 prokinetic 药物更少. 需要进一步的高质量试验来证实这些研究结果对FD治疗.
科学领域:
- 胃肠病学 胃肠病学
- 草药是一种草药.
- 系统性审查和元分析
背景情况:
- 功能性消化不良 (FD) 影响全球约15%的未知原因.
- 草药为FD提供了多方面的治疗潜力.
- 西霍吉吉唐 (Shogyeji-tang,SG) 是一种传统的草药.
研究的目的:
- 为了建立医疗证据,Shogyeji-tang (SG) 在治疗FD.
- 为患者和医疗保健从业人员提供临床相关证据.
- 综合了对FD的SG随机对照试验 (RCT) 的研究结果.
主要方法:
- 进行全面的数据库搜索 (PubMed,EMBASE,Cochrane等) 在2025年6月24日进行.
- 包括12个RCT,805名参与者调查了FD的SG.
- 使用Cochrane工具评估偏差风险;使用审查经理合成数据 5.4.4.
主要成果:
- SG显示总有效率明显高于原动力学药物 (RR: 1.28,95% CI: 1.19-1.37).
- SG显著降低了症状严重程度 (SMD: -1.10,95% CI: -1.53至-0.68) 与较低的不良事件发生率 (RR: 0.26,95% CI: 0.09-0.76).
- 证据质量对于疗效来说中等,对于症状得分和不良事件来说低.
结论:
- 对于FD,SG似乎比原动力学药物更有效,更安全.
- 当前研究中的方法论缺陷限制了证据的确定性.
- 需要高质量的RCT来验证SG在FD的临床使用.
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