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相关概念视频

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

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Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
185
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

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A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
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Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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Disorders of Hemostasis01:24

Disorders of Hemostasis

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Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
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状细胞病:管理血栓栓塞的方法

Kavya Babu1, Ted Wun1

  • 1Division of Hematology and Oncology, Department of Internal Medicine, UC Davis Comprehensive Cancer Center, Sacramento, CA.

Hematology. American Society of Hematology. Education Program
|December 5, 2025
PubMed
概括

状细胞疾病 (SCD) 增加了由于凝血变化而导致血栓形成的风险. 血栓预防和抗凝剂,如直接口服抗Xa抗剂,对于这些患者的静脉血栓塞栓症 (VTE) 管理至关重要.

科学领域:

  • 血液学 血液学 血液学
  • 血管医学 血管医学
  • 药理学 药理学是指药理学的学科.

背景情况:

  • 状细胞疾病 (SCD) 呈现为一种获得的高凝血状态.
  • SCD涉及前血栓凝血变化,血小板活化升高和内皮损伤.
  • 这些病理变化与更高的静脉血栓塞栓症 (VTE) 发病率相关.

研究的目的:

  • 探索初级血栓预防在状细胞病患者中的作用.
  • 调查血栓预防策略,特别是关于中央静脉导管的使用.
  • 在特定高风险时期检查预防:术前,晚期怀孕和产后.

主要方法:

  • 对SCD中血栓预防现有文献的综述.
  • 对SCD患者的抗凝剂使用模式的分析VTE.
  • 治疗策略与一般VTE人群的比较.

主要成果:

  • 直接口服抗Xa抗剂越来越多地用于SCD患者的VTE的二次预防.
  • 对于SCD中特定的高风险场景,正在考虑初级血栓预防.
  • 在SCD中高凝血状态需要仔细管理VTE风险.

结论:

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  • 由于复杂的血液和血管变化,SCD患者具有显著的VTE风险.
  • 抗凝固药物治疗,包括直接的口服抗Xa抗剂,在二次VTE预防中起着至关重要的作用.
  • 对于特定的高风险SCD患者群体,对初级血栓预防的进一步研究是有必要的.