使用前段光学连贯断层扫描和Scheimpflug成像,在角膜眼中加速角膜交叉连接后,对角膜平衡演变的比较
Antonia Lang1, Berthold Seitz2, Cristian Munteanu2
1Department of Ophthalmology, Saarland University Medical Center, Kirrberger Straße, Building 22, 66424, Homburg, Germany. anla00014@stud.unisaarland.de.
International ophthalmology
|December 5, 2025
概括
Pentacam HR Scheimpflug成像检测到角膜在加速角膜交叉连接 (A-CXL) 后角膜稀薄,但Casia 2 AS-OCT没有. 这些测量设备对于监测A-CXL结果是不可互换的.
科学领域:
- 眼科医生 眼科 眼科
- 角质科学 角质科学
- 医疗成像医学成像
背景情况:
- 角膜 (KC) 是角膜逐渐变薄的疾病.
- 加快角膜交叉连接 (A-CXL) 是一种治疗方法,用于硬角膜并阻止KC的进展.
- 精确的精度测量对于监测治疗疗效至关重要.
研究的目的:
- 为了比较A-CXL后使用Pentacam HR (Scheimpflug) 和Casia 2 (AS-OCT) 的纵向角膜平衡测量.
- 评估这两种成像方法在测量A-CXL后的中央 (CCT) 和最薄 (TCT) 角膜厚度时的一致性.
主要方法:
- 对218个用A-CXL治疗的KC眼睛进行了回顾性研究.
- 用Pentacam HR和Casia 2在多个时间点测量角膜厚度,直到最近的随访.
- 在A-CXL期间用于监测CCT的手术内超声波平衡.
主要成果:
- 在A-CXL后,Pentacam HR显示出显著的CCT和TCT减少,而Casia 2则没有.
- 在A-CXL后六周观察到设备之间的最高测量一致性.
- 角膜密度测量在六周达到峰值,然后下降,但没有达到A-CXL前的水平.
结论:
- 在A-CXL之后,Pentacam HR和Casia 2的精度测量是不可互换的.
- 在A-CXL之后,基于Scheimpflug的厚度测量需要谨慎的解释,特别是在第一年.
- 由Pentacam HR观察到的角膜变薄,Casia 2没有检测到,突出了设备特异性的差异.
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