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在一个大型综合医疗保健系统中,气候脆弱性指数和2型糖尿病的发生率
Jad Ardakani1, Izza Shahid1, Rakesh Gullapelli1
1Center for Cardiovascular Computational and Precision Health (C3PH), Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas.
社区中较高的气候脆弱性增加了2型糖尿病 (T2D) 的风险. 这项研究发现,居住在气候脆弱性高的地区 (CVI) 与患T2D的风险更高有关,即使考虑到其他风险因素.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 代谢疾病研究研究
背景情况:
- 基于地点的气候脆弱性指数 (CVI) 可能通过环境和社会经济因素影响代谢风险.
- CVI与发生型2型糖尿病 (T2D) 之间的关联需要进一步描述.
研究的目的:
- 调查居住在CVI较高的社区是否与发生T2D的风险增加有关.
主要方法:
- 这是一项回顾性队列研究,利用了休斯顿卫理教学习卫生系统注册局 (Houston Methodist Learning Health System Registry) 的数据 (2016年6月-2023年8月).
- 包括在基线没有T2D的100多万成年人,分析了美国人口普查通道水平的CVI,分为四分之一.
- 事件T2D是通过ICD代码,处方或HbA1c水平来识别的;调整的危险比率 (HRs) 被计算出来.
主要成果:
- 在1,003,526名参与者中,有40,152人患有T2D.
- 糖尿病发病率在最高的CVI四分位数 (Q4) 中高于最低的 (Q1) (2.66对1.48例/100人年).
- 居住在Q4 CVI地区与Q1.36相比,与T2D风险增加23%有关 (HR,1.23;95% CI,1.11-1.36).
结论:
- 更高的社区CVI独立地与发生T2D的风险增加有关.
- 将地理编码的CVI与电子健康记录相结合,可以帮助有针对性的预防和人口健康规划.
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