在庞贝老鼠中,疾病进展的呼吸系统特征

Alyssa R Mickle1,2,3, Sabhya Rana2,3,4, Ethan S Benevides2,3,4

  • 1Department of Neuroscience, University of Florida, 1149 Newell Dr, Gainesville, FL 32610.

PubMed
概括

佩氏病早期发病导致由于酸α-葡萄糖酶 (GAA) 缺乏而引起的呼吸系统问题. 一种老鼠模型显示出明显的"呼吸信号",表明神经肌肉的逐渐衰退,这对于评估治疗非常有用.

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