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Updated: Jan 9, 2026

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整合单细胞生物物理和转录基因特征,以解决地幔细胞淋巴瘤的功能异质性

Ye Zhang1, Lydie Debaize2, Adam Langenbucher3

  • 1Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.

Science advances
|December 5, 2025
PubMed
概括

单细胞生物物理特性,如浮力质量和性,可以识别癌细胞表型. 这些特性与治疗反应相关,为B细胞恶性瘤的精准医学提供了新的生物标志物.

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Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
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