与保持比率受损的螺旋测量相关的年龄相关因素:东北医疗Megabank项目基于社区的队列研究
Chikashi Iwasaki1, Kumi Nakaya2, Mitsuhiro Yamada3
1Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan; Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan; Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8573, Japan.
保持比率受损螺旋计 (PRISm) 根据年龄不同. 患有PRISm的年轻人与甲状腺功能低下和低BMI有关,而老年人与生活方式因素和其他疾病有关.
科学领域:
- 肺部医学 肺部医学
- 流行病学 流行病学
- 老年学是指老年学的学科.
背景情况:
- 保留比率受损螺旋计 (PRISm) 与健康状况不佳有关,但其决定因素,特别是年轻人群,尚不清楚.
- 了解PRISm的关联对于有针对性的干预和改善患者管理至关重要.
- 这项研究调查了与PRISm相关的因素,涉及不同年龄的人口结构.
研究的目的:
- 在一个日本社区的队列中,确定与保留比率受损螺旋测量 (PRISm) 相关的因素.
- 探索PRISm的决定因素中的特定年龄的差异.
- 调查与PRISm相关的年龄和其他变量之间的相互作用.
主要方法:
- 对来自东北医疗大银行项目的12350名参与者的横截面分析.
- 数据收集包括螺旋计,血压,实验室测试和问卷.
- 多变量逻辑回归分析了跨年龄组 (20-39岁,40-59岁,≥60岁) 的PRISM关联.
主要成果:
- 在年轻的成年人 (20-39岁) 中,PRISm与男性性别,糖尿病,甲状腺功能低下和低BMI有关.
- 在老年人 (≥60岁) 中,PRISm与年龄的增加,超重,男性性别,吸烟,高血压,糖尿病,喘,高乙酸细胞和特定出生体重有关.
- 在年龄和BMI,喘和甲状腺功能障碍之间发现了显著的相互作用.
结论:
- 根据年龄组,PRISm的决定因素有很大的不同.
- 甲状腺功能低下和体重不足是患有PRISm的年轻人中的关键因素.
- 在患有PRISM的老年人中,生活方式和身体因素更为突出,这表明了特定于年龄的管理策略.
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