坚持MIND饮食和出现神经髓炎光学谱系障碍:一个病例控制研究
Sanaz Khodadadi1, Nasim Rezaeimanesh1, Morvarid Noormohammadi2
1Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Multiple sclerosis and related disorders
|December 5, 2025
概括
富含大脑健康食品的MIND饮食与发展神经髓炎光学谱系障碍 (NMOSD) 的风险降低有关. 更高的MIND饮食坚持,包括特定的食物组,显示出与较低的NMOSD几率有显著的关联.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 免疫学 免疫学 免疫学
背景情况:
- MIND饮食结合了地中海和DASH饮食,以增强大脑功能和延迟神经退行性疾病.
- 神经脊髓炎光学谱系障碍 (NMOSD) 是一种罕见的自身免疫性疾病,影响中枢神经系统.
研究的目的:
- 研究坚持MIND饮食与患NMOSD的风险之间的潜在关联.
- 在MIND饮食中确定可能影响NMOSD发病的特定食物组.
主要方法:
- 一项基于医院的病例控制研究,涉及68名NMOSD患者和136名对照.
- 通过168项食品频率问卷 (FFQ) 收集的饮食摄入数据,用于入学前一年.
- 后勤回归分析用于确定MIND饮食遵守与NMOSD风险之间的关联,结果以调整的几率比率 (AOR) 呈现.
主要成果:
- 更高的MIND饮食坚持与较低的NMOSD风险显著相关.
- 坚持MIND饮食的高三级参与者显示,NMOSD的几率降低了 (T2 AOR=0.18,T3 AOR=0.23).
- 绿叶蔬菜,豆类,全谷物,橄油,家禽和果等特定食物组与NMOSD风险相反相关.
结论:
- MIND饮食,以及蔬菜,全谷物,豆类,橄油,果和家禽等关键成分,似乎降低了神经髓炎光学谱系疾病的风险.
- 研究结果表明,MIND饮食在NMOSD的背景下具有神经保护作用.
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