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成年患者患有先天性心脏病的感染性内心炎
Andrés Alonso-Garcia1, Nuria Fernandez-Hidalgo2, Victor Gonzalez-Fernandez3
1Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain; Unidad de Cardiopatías Congénitas del Adulto; Departamento de Cardiología, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.
The Canadian journal of cardiology
|December 5, 2025
概括
患有先天性心脏病 (CHD) 的成年人面临感染性内心炎 (IE),一种严重感染的风险明显更高. 这凸显了对这种不断增长的患者群体提高认识和预防策略的必要性.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 儿科心脏病学和心脏外科手术的进步导致了患有先天性心脏病 (CHD) 的成年人越来越多.
- 患有心血管疾病的成年人的存活率现在超过95%.
- 尽管存活率有所改善,但患有心脏病的成年人患有感染性内心炎 (IE) 的发生率大幅增加.
研究的目的:
- 突出感染性内心炎 (IE) 在患有先天性心脏病 (CHD) 的成人中增加的风险和影响.
- 强调CHD作为IE的主要风险因素的重要性,特别是在高收入国家的儿科人口中.
主要方法:
- 文献综述和流行病学数据的综合IE发病率在心血管疾病群体.
- 对心血管疾病患者与普通人群中IE患病率的比较分析.
- 检查与年龄相关的因素和IE在心脏病中的风险分层.
主要成果:
- 患有心血管疾病的成年人中IE的发病率为每1000人/年1-19例,比普通人群增加30倍.
- IE占所有IE病例的6-10%,呈现的中位数年龄较小 (约30岁).
- 在高收入国家的儿科人口中,先天性心脏病是IE的主要风险因素.
结论:
- 患有先天性心脏病的成年人代表了一个脆弱的人群,感染性内心炎的负担很高.
- 先天性心脏病是IE的关键风险因素,需要有针对性的预防和管理策略.
- 成年人患有冠状动脉疾病的患病率不断上升,凸显了在这个人口群体中解决IE风险的重要性.
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