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Updated: Jan 9, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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Published on: February 20, 2018

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大脑G蛋白Go与其潜在效应物RASA3的结合是由Ca2促进的

Halie A S Bell1, Andrew C Olson1, Juliana E Gentile1

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, USA.

The Journal of biological chemistry
|December 5, 2025
PubMed
概括

研究人员确定RASA2和RASA3是大脑Gαo信号传递的新型效应器. 这些蛋白质直接与Gαo结合,调解其对神经功能的抑制作用.

关键词:
这是一种GTPase激活蛋白 (GAP).G (((o) 的意思是在RASA3中,RASA3是指RASA3,RASA3是指RASA3.异构三基的G蛋白质.神经递质信号传输神经递质信号传输蛋白质蛋白质相互作用蛋白质组学 蛋白质组学

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