相关实验视频

Updated: Jan 9, 2026

Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source
08:35

Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source

Published on: May 29, 2021

6.8K

通过基于结构的虚拟查来识别甲基受体1抑制剂

Yi-Hsuan Wang1, Tony Eight Lin2, Yu-Cheng Chen3

  • 1Graduate Institute of Natural Products and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Biochemical pharmacology
|December 5, 2025
PubMed
概括

研究人员确定668429化合物是甲基受体1 (FPR1) 的强有力的抑制剂,甲基受体1 (FPR1) 是中性粒细胞驱动炎症的关键标. 这种选择性抑制剂对开发用于炎症疾病的新疗法充满希望.

关键词:
一个叫FPR的F1炎症 炎症是一种炎症.作为一个中性粒细胞.小分子抑制剂小分子抑制剂基于结构的虚拟选.

更多相关视频

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library07:32

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library

Published on: September 30, 2019

8.2K
Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions08:31

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

Published on: December 1, 2020

5.5K

相关概念视频

G Protein-coupled Receptors01:15

G Protein-coupled Receptors

G Protein-Coupled Receptors or GPCRs are membrane-bound receptors that transiently associate with heterotrimeric G proteins and induce an appropriate response to sensory stimuli such as light, odors, hormones, cytokines, or neurotransmitters.
GPCRs are also called heptahelical, 7TM, or serpentine receptors, and consist of seven (H1-H7) transmembrane alpha-helices that span the bilayer to form a cylindrical core. The transmembrane helices are connected by three extracellular loops and three...
16.3K