副 (槽) 胰腺炎的临床特征和演变:一项多中心研究
Giacomo Emanuele Maria Rizzo1, Matteo Tacelli2, Stefano Francesco Crinò3
1Gastroenterology and Endoscopy Unit, Istituto Mediterraneo per i Trapianti e Terapie di alta specializzazione - IRCCS ISMETT, Palermo, Italy; University of Pittisburgh Medical Center Italy (UPMC Italy), Palermo, Italy.
概括
腹炎 (PP) 与酒精和吸烟有很强的联系. 许多患者患上糖尿病和胰腺外分泌功能不全 (PEI),但保守的治疗通常对这种罕见的疾病有效.
科学领域:
- 胃肠病学 胃肠病学
- 胰腺学 胰腺学
- 临床医学 临床医学
背景情况:
- 腹 (槽) 胰腺炎 (PP) 的发病因子和自然史尚不清楚.
- 目前对PP的治疗选择包括药物治疗,干预内镜和手术.
研究的目的:
- 为了调查甲炎 (PP) 的疾病负担.
- 探索PP患者的临床过程和治疗反应.
主要方法:
- 来自意大利学术和非学术中心的回顾性数据收集.
- 包括所有被诊断为PP的患者.
- 在诊断和随访期间记录数据.
主要成果:
- 从16个中心招募了208名患者 (87.5%是男性).
- 主要的危险因素包括滥用酒精 (90.6%) 和吸烟 (90.7%).
- 糖尿病 (17.9%) 和胰腺外分衰竭 (PEI) (24.9%在诊断时,24.3%在随访期间发展) 是常见的并发症. 在3%的患者中诊断出胰腺癌.
结论:
- 饮酒和吸烟被确定为PP的主要危险因素.
- 糖尿病和PEI经常发生在PP患者中.
- 保守的治疗方法在管理PP时显示出显著的成功率.
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