可生物降解的胰腺支架在ERCP后胰腺炎预防中的成本效益
Abdullah Abbasi1, Raheel Anjum2, Pavit Tewatia3
1University of Iowa Health Care, 200 Hawkins Drive, Iowa City, Iowa, 52242, USA.
概括
可生物降解的胆胰腺支架 (BDS) 是传统胰腺支架 (PS) 的经济有效替代品,用于预防ERCP后胰腺炎. 使用BDS消除了对随访程序的需求,改善了患者的治疗结果,并降低了医疗保健成本.
科学领域:
- 胃肠病学 胃肠病学
- 卫生经济学 卫生经济学
- 医疗器械 医疗器械
背景情况:
- 可生物降解的胆腺支架 (BDS) 通过消除后续程序,比传统支架提供潜在的经济优势.
- 然而,BDS用于预防ERCP后胰腺炎 (PEP) 的成本效益尚未先前评估.
- 这项研究通过在健康经济模型中将传统的胰腺支架 (PS) 与BDS进行比较来弥补这一差距.
研究的目的:
- 开发一个健康经济模型,比较可生物降解胆胰腺支架 (BDS) 与常规胰腺支架 (PS) 的成本效益.
- 该模型专门评估了ERCP后胰腺炎 (PEP) 的预防.
主要方法:
- 使用皇家沃尔弗汉普顿NHS信托基金的数据开发了一个成本效益决策分析模型.
- 生命质量数据 (效用值) 来自现有文献.
- 进行了决定性和概率性灵敏度分析,计算增量成本效益比率 (ICERs) 与30,000英的支付意愿门相比.
主要成果:
- 确定性分析表明,与PS (£377.59, 0.95 QALY) 相比,BDS对PEP预防具有成本效益 (£656.12, 0.98 QALY),其ICER为£9316.70.
- 概率灵敏度分析证实BDS是更具成本效益的选择.
- 为了使BDS保持成本效益,确定了353.37英的成本门.
结论:
- 与传统的胰腺支架 (PS) 相比,生物降解性胰腺支架 (BDS) 是PEP预防的成本有效策略.
- 使用BDS可以避免需要进行后续成像和重复切除支架的程序,提高效率和患者护理.
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