相关实验视频
Updated: Jul 9, 2026
10:26
Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
12.8K
顶端制剂大小和被动超声波激活对带有周边损伤的根通道中的微生物负荷的影响
Melike Yavuz1, Tan Fırat Eyuboglu2, Seyda Ersahan Eroglu1
1Department of Endodontics, Faculty of Dentistry, Istanbul Medipol University, Cibali Mahallesi, Atatürk Bulvari, No: 27, 34083, Istanbul, Turkey.
Scientific reports
|December 5, 2025
概括
微创和传统的根运河扩张都有效地减少了超过95%的内运河细菌. 然而,持久的Enterococcus faecalis和Pseudomonas突出了加强消毒策略的必要性.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 微生物学 微生物学
- 牙科治疗学 牙科治疗学
背景情况:
- 周周病变常常包含复杂的微生物群落.
- 有效的管内消毒对于成功的根管治疗结果至关重要.
- 形扩大技术和灌激活影响细菌的减少.
研究的目的:
- 为了比较微侵袭和传统的角扩大方法之间的内细菌减少.
- 评估塑造尺寸和灌激活对细菌负载的影响.
- 在根管治疗后识别持久的微生物物种.
主要方法:
- 一项随机研究,涉及24名患有周围病变的患者.
- 两组:最小侵入性 (25/0.04) 和常规的 (35/0.04) 顶部扩大.
- 处理前后收集的细菌样本;通过滴滴数字PCR量化,并通过测序识别.
- 用于激活的被动超声波灌 (PUI).
主要成果:
- 这两种技术都实现了超过95%的细菌减少 (p < 0.01),群体之间没有显著差异.
- 传统扩大显示出更高的基线疼痛得分 (p=0.042),但术后疼痛是相似的.
- 伪omonas spp. 这种类型的. 在常规组中,治疗前更为普遍 (p=0.048).
结论:
- 这两种角扩大方法都显著减少了内细菌.
- Enterococcus faecalis和Pseudomonas物种表现出对当前协议的耐药性.
- 改善的消毒和激活技术是必要的,以消除持久的生物膜.
相关概念视频
01:12Local Anesthetics: Adverse Effects
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
01:28Antimicrobial Effectiveness
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...